Structure of PDB 6id0 Chain J

Receptor sequence
>6id0J (length=556) Species: 9606 (Homo sapiens) [Search protein sequence]
VKNKAPAEVQITAEQLLREAKERELELLPPPPQQKITDEEELNDYKLRKR
KTFEDNIRKNRTVISNWIKYAQWEESLKEIQRARSIYERALDVDYRNITL
WLKYAEMEMKNRQVNHARNIWDRAITTLPRVNQFWYKYTYMEEMLGNVAG
ARQVFERWMEWQPEEQAWHSYINFELRYKEVDRARTIYERFVLVHPDVKN
WIKYARFEEKHAYFAHARKVYERAVEFFGDEHMDEHLYVAFAKFEENQKE
FERVRVIYKYALDRISKQELFKNYTIFEKKFGDRRGKRRFQYEEEVKANP
HNYDAWFDYLRLVESDAEAEAVREVNVPPIQEKRHWKRYIYNYALYEELE
AKDPERTRQASLELIPHKKAKMWILYAQFEIRQSLARRALGTSIGKLFKV
YIELELQLREFDRKFLEFGPENCTSWIELETILGDIDRARLAISQPRLDM
PEVLWIDFEIEQEETERTRNYRRLLQRTQHVKVFELSSGKEGSLTKNKTM
RNCEEKEERLMLLESFEEEFGTASDKERVDKLMEKVKKRRKVQTDDGSDA
GWEEYF
3D structure
PDB6id0 Structures of the human spliceosomes before and after release of the ligated exon.
ChainJ
Resolution2.9 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna J R236 K237 S243 T277 K281 K315 R58 K59 S65 T99 K103 K137
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0000245 spliceosomal complex assembly
GO:0000398 mRNA splicing, via spliceosome
GO:0006396 RNA processing
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0000974 Prp19 complex
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005681 spliceosomal complex
GO:0016607 nuclear speck
GO:0071007 U2-type catalytic step 2 spliceosome
GO:0071013 catalytic step 2 spliceosome
GO:0071014 post-mRNA release spliceosomal complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6id0, PDBe:6id0, PDBj:6id0
PDBsum6id0
PubMed30728453
UniProtQ9BZJ0|CRNL1_HUMAN Crooked neck-like protein 1 (Gene Name=CRNKL1)

[Back to BioLiP]