Structure of PDB 6ft6 Chain J

Receptor sequence

>6ft6J (length=169) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]

QNPMRDLKIEKLVLNISVGESGDRLTRASKVLEQLSGQTPVQSKARYTVR
TFGIRRNEKIAVHVTVRGPKAEEILERGLKVKEYQLRDRNFSATGNFGFG
IDEHIDLGIKYDPSIGIFGMDFYVVMNRPGARVTRRKRCKGTVGNSHKTT
KEDTVSWFKQKYDADVLDK

3D structure

PDB

6ft6 Structure of the nuclear exosome captured on a maturing preribosome.

Chain

Resolution

3.9 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	J	V18 N20 S22 S48 R51 Y52 R55 T56 F57 R61 A66 R94 N95 F96 S97 A98 N101 G103 F104 G105 I106 D107 G124 M125 D126 Y128 V130	V13 N15 S17 S43 R46 Y47 R50 T51 F52 R56 A61 R89 N90 F91 S92 A93 N96 G98 F99 G100 I101 D102 G119 M120 D121 Y123 V125
BS02	rna	J	P8 M9 R10 Q43 T44 T70 R72 G135 R137 R140 R141 R143 T147 V148 G149 H152	P3 M4 R5 Q38 T39 T65 R67 G130 R132 R135 R136 R138 T142 V143 G144 H147

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding

	Biological Process
GO:0000027	ribosomal large subunit assembly
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:6ft6, PDBe:6ft6, PDBj:6ft6
PDBsum	6ft6
PubMed	29519915
UniProt	P0C0W9\|RL11A_YEAST Large ribosomal subunit protein uL5A (Gene Name=RPL11A)

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