Structure of PDB 6bcg Chain J

Receptor sequence

>6bcgJ (length=282) Species: 330483 (Leptographium truncatum) [Search protein sequence]

NISPWTITGFADGESSFMLTVSKDKRNTGWSVRPRFRIGLHNKDVTILKS
IREYLGAGIITSDIDARIRFESLKELEVVINHFDKYPLITQKRADYLLFK
KAFYLIKNKEHLTEEGLNQILTLKASLNLGLSEELKEAFPNTIPAEQEIP
DSNWVAGFTAGEGSFYIRIAKNSTLKTGYQVQSVFQITQDTRDIELMKNL
ISYLNCGNIRIRTCVDLVVTNLNDIKEKIIPFFNKNHIIGVKLQDYRDWC
KVVTLIDNKEHLTSEGLEKIQKIKEGMNRGRS

3D structure

PDB

6bcg Active site residue identity regulates cleavage preference of LAGLIDADG homing endonucleases.

Chain

Resolution

2.9 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	J	E29 S31 M33 R51 R53 K108 N144 L145 T196 L197 K198 Q202 Q204 N230 R234 L254 H293	E14 S16 M18 R35 R37 K92 N128 L129 T174 L175 K176 Q180 Q182 N208 R212 L222 H261
BS02	dna	J	K41 R49 R83 R85 E87 S88 L89 H127 L128 S186 A192 K193 Q208 D212 R234 N310 R311	K25 R33 R67 R69 E71 S72 L73 H111 L112 S164 A170 K171 Q186 D190 R212 N278 R279
BS03	CA	J	E29 G183	E14 G161

Gene Ontology

	Molecular Function
GO:0004519	endonuclease activity

View graph for
Molecular Function

External links

PDB	RCSB:6bcg, PDBe:6bcg, PDBj:6bcg
PDBsum	6bcg
PubMed	30357419
UniProt	C7SWF3

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