Structure of PDB 5ylz Chain J

Receptor sequence
>5ylzJ (length=432) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
KGGVWTNVEDQILKAAVQKYGTHQWSKVASLLQKKTARQSELRWNEYLNP
KLNFTEFSKEEDAQLLDLARELPNQWRTIADMMARPAQVCVERYNRLLES
EDSEDEEKEMLAEARARLLNTQGKKATRKIRERMLEESKRIAELQKRREL
KQAGINVAIKKPKKKYGTDIDYNEDIVYEQAPMPGIYDTSTEDRQIKKKF
EQFERKVNRKGLLTPKELLPHDSGQEDNERSNIKSGKQLKSRIRKFFASL
PSPKNDFEIEDEKEEDAEIAEYEKEEDNFIEPPSQPRVSLVAVPLAYSTL
KNNPQSAIDNKYNLLVANAINKEPHMESRMQHITQGRTSMKIQFKTAMPP
TEVLLESIQSKVESIEQLQRKLQHVQPLEQQNNEMCSTLCHHSLPALIEG
QRKYYADYYAYRQEIRSLEGRRKRLQAMLNSS
3D structure
PDB5ylz Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae
ChainJ
Resolution3.6 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna J Y28 K35 R158 K165 Y207 Y219 Y20 K27 R117 K124 Y166 Y178
BS02 rna J E147 K204 E106 K163
Gene Ontology
Molecular Function
GO:0000386 second spliceosomal transesterification activity
GO:0003677 DNA binding
GO:0005515 protein binding
Biological Process
GO:0000350 generation of catalytic spliceosome for second transesterification step
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0000974 Prp19 complex
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005737 cytoplasm
GO:0071006 U2-type catalytic step 1 spliceosome

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5ylz, PDBe:5ylz, PDBj:5ylz
PDBsum5ylz
PubMed29153833
UniProtQ03654|CEF1_YEAST Pre-mRNA-splicing factor CEF1 (Gene Name=CEF1)

[Back to BioLiP]