Structure of PDB 5yj1 Chain J

Receptor sequence
>5yj1J (length=91) Species: 10090 (Mus musculus) [Search protein sequence]
TSLCCKQCQETEITTKNEIFSLSHETLTVYKASNLNLIGRPSTVHSWFPG
YAWTIAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLP
3D structure
PDB5yj1 Structural basis of thalidomide enantiomer binding to cereblon
ChainJ
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 6EL J H381 W383 W389 W403 F405 H45 W47 W53 W67 F69 MOAD: Kd=50.3uM
BS02 ZN J C326 C329 C394 C397 C5 C8 C58 C61
External links
PDB RCSB:5yj1, PDBe:5yj1, PDBj:5yj1
PDBsum5yj1
PubMed29358579
UniProtQ8C7D2|CRBN_MOUSE Protein cereblon (Gene Name=Crbn)

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