Structure of PDB 5yj0 Chain J

Receptor sequence
>5yj0J (length=91) Species: 10090 (Mus musculus) [Search protein sequence]
TSLCCKQCQETEITTKNEIFSLSHETLTVYKASNLNLIGRPSTVHSWFPG
YAWTIAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLP
3D structure
PDB5yj0 Structural basis of thalidomide enantiomer binding to cereblon
ChainJ
Resolution1.8 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 EF2 J H381 S382 W383 W389 W403 F405 H45 S46 W47 W53 W67 F69 MOAD: Kd=5.7uM
BS02 ZN J C326 C329 C394 C397 C5 C8 C58 C61
External links
PDB RCSB:5yj0, PDBe:5yj0, PDBj:5yj0
PDBsum5yj0
PubMed29358579
UniProtQ8C7D2|CRBN_MOUSE Protein cereblon (Gene Name=Crbn)

[Back to BioLiP]