Structure of PDB 5xjc Chain J

Receptor sequence
>5xjcJ (length=571) Species: 9606 (Homo sapiens) [Search protein sequence]
VKNKAPAEVQITAEQLLREAKERELELLPPPPQQKITDEEELNDYKLRKR
KTFEDNIRKNRTVISNWIKYAQWEESLKEIQRARSIYERALDVDYRNITL
WLKYAEMEMKNRQVNHARNIWDRAITTLPRVNQFWYKYTYMEEMLGNVAG
ARQVFERWMEWQPEEQAWHSYINFELRYKEVDRARTIYERFVLVHPDVKN
WIKYARFEEKHAYFAHARKVYERAVEFFGDEHMDEHLYVAFAKFEENQKE
FERVRVIYKYALDRISKQELFKNYTIFEKKFGDRRGKRRFQYEEEVKANP
HNYDAWFDYLRLVESDAEAEAVREVNVPPIQEKRHWKRYIYWINYALYEE
LEAKDPERTRQASLELIPHKKAKMWILYAQFEIRQKLSARRALGTSIGKC
PKKLFKVYIELELQLREFDREKFLEFGPENCTSWIELETILGDIDRARLA
ISQPRLDMPEVLWIDFEIEQEETERTRNYRRLLQRTQHVKVIFAFELSSG
KEGSLTKCRQINKTMRNCEEKEERLMLLESFEEEFGTASDKERVDKLMEK
VKKRRKVQTDDGSDAGWEEYF
3D structure
PDB5xjc An Atomic Structure of the Human Spliceosome
ChainJ
Resolution3.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna J R236 K237 K247 N275 T277 K315 R58 K59 K69 N97 T99 K137
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0000245 spliceosomal complex assembly
GO:0000398 mRNA splicing, via spliceosome
GO:0006396 RNA processing
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0000974 Prp19 complex
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005681 spliceosomal complex
GO:0016607 nuclear speck
GO:0071007 U2-type catalytic step 2 spliceosome
GO:0071013 catalytic step 2 spliceosome
GO:0071014 post-mRNA release spliceosomal complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5xjc, PDBe:5xjc, PDBj:5xjc
PDBsum5xjc
PubMed28502770
UniProtQ9BZJ0|CRNL1_HUMAN Crooked neck-like protein 1 (Gene Name=CRNKL1)

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