Structure of PDB 5tzd Chain J

Receptor sequence
>5tzdJ (length=75) Species: 953739 (Streptomyces venezuelae ATCC 10712) [Search protein sequence]
KLVLDLERMAHVPQEKAGPLQRYAATIQSQRGDYNGKVLSIRQDDLRTLA
VIYDQSPSVLTEQLISWGVLDADAR
3D structure
PDB5tzd The Streptomyces master regulator BldD binds c-di-GMP sequentially to create a functional BldD2-(c-di-GMP)4 complex.
ChainJ
Resolution1.749 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 C2E J K84 R114 S123 R125 Q126 K1 R31 S40 R42 Q43 PDBbind-CN: -logKd/Ki=5.74,Kd=1.8uM
BS02 C2E J I110 Q113 R114 R125 D128 I27 Q30 R31 R42 D45 PDBbind-CN: -logKd/Ki=5.74,Kd=1.8uM
Gene Ontology
Biological Process
GO:0045892 negative regulation of DNA-templated transcription

View graph for
Biological Process
External links
PDB RCSB:5tzd, PDBe:5tzd, PDBj:5tzd
PDBsum5tzd
PubMed28449057
UniProtF2RCL8

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