Structure of PDB 5t16 Chain J

Receptor sequence
>5t16J (length=267) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
DPTKAGDIVKATKWPPKLPEIQDLAIRARVFIHKSTIKDKVYLSGSEMIN
AHNERLEFLGDSILNSVMTLIIYNKFPDYSEGQLSTLRMNLVSNEQIKQW
SIMYNFHEKLKTNFDLKDENSNFQNGKLKLYADVFEAYIGGLMEDDPRNN
LPKIRKWLRKLAKPVIEEATRNQVKLDMNAKRQLYSLIGYASLRLHYVTV
KKPTAVDPNSIVECRVGDGTVLGTGVGRNIKIAGIRAAENALRDKKMLDF
YAKQRAAIPRSESVLKD
3D structure
PDB5t16 The Functional Cycle of Rnt1p: Five Consecutive Steps of Double-Stranded RNA Processing by a Eukaryotic RNase III.
ChainJ
Resolution2.783 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.26.3: ribonuclease III.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna J H217 K218 K222 F298 N306 F307 K311 H33 K34 K38 F114 N122 F123 K127
BS02 rna J T270 M273 K371 R372 Y375 S376 G379 Y380 A381 N419 I420 K421 R445 R450 S453 V454 K456 T86 M89 K181 R182 Y185 S186 G189 Y190 A191 N229 I230 K231 R255 R260 S263 V264 K266
Gene Ontology
Molecular Function
GO:0003725 double-stranded RNA binding
GO:0004525 ribonuclease III activity
Biological Process
GO:0006364 rRNA processing
GO:0006396 RNA processing

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Molecular Function
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Biological Process
External links
PDB RCSB:5t16, PDBe:5t16, PDBj:5t16
PDBsum5t16
PubMed28111020
UniProtQ02555|RNT1_YEAST Ribonuclease 3 (Gene Name=RNT1)

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