Structure of PDB 5m45 Chain J

Receptor sequence
>5m45J (length=762) Species: 78245 (Xanthobacter autotrophicus Py2) [Search protein sequence]
RGIVRGGETLKEHRDRLMAATKATGRYAGLKTLELREREPILYNKLFSRL
RAGVVDARETAKKIAASPIVEQEGELCFTLYNAAGDSLLTSTGIIIHVGT
MGAAIKYMIENNWEANPGVHDKDIFCNNDSLIGNVHPCDIHTIVPIFWEG
ELIGWVGGVTHVIDTGAVGPGSMATGQVQRFGDGYSITCRKVGANDTLFR
DWLHESQRMVRTTRYWMLDERTRIAGCHMIRKLVEEVVAEEGIEAYWKFA
YEAVEHGRLGLQARIKAMTIPGTYRQVGFVDVPYAHEDVRVPSDFAKLDT
IMHAPCEMTIRRDGTWRLDFEGSSRWGWHTYNAHQVSFTSGIWVMMTQTL
IPSEMINDGAAYGTEFRLPKGTWMNPDDRRVAFSYSWHFLVSAWTALWRG
LSRSYFGRGYLEEVNAGNANTSNWLQGGGFNQYDEIHAVNSFECAANGTG
ATAVQDGLSHAAAIWNPEGDMGDMEIWELAEPLVYLGRQIKASSGGSGKY
RGGCGFESLRMVWNAKDWTMFFMGNGHISSDWGLMGGYPAASGYRFAAHK
TNLKELIASGAEIPLGGDTDPENPTWDAMLPDAQIKRDKQAITTEEMFSD
YDLYLNYMRGGPGFGDPLDREPQAVADDINGGYVLERFAGEVYGVVVRKG
ADGQYGVDETATAAARAQIRKDRLAKSVPVSEWMKGEREKILAKDAGTQV
RQMFAASFKLGPRFEKDFRTFWDLPDSWTLPEEEIGVPTYGSRYSMDISE
LPDVHTVQFVEE
3D structure
PDB5m45 Structural Basis for the Mechanism of ATP-Dependent Acetone Carboxylation.
ChainJ
Resolution1.87 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.4.1.6: acetone carboxylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN J H150 D153 H175 H136 D139 H161
BS02 ACT J H150 H175 W401 W479 H136 H161 W387 W465
BS03 MG J S763 V768 S749 V754
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016874 ligase activity
GO:0017168 5-oxoprolinase (ATP-hydrolyzing) activity
GO:0018710 acetone carboxylase activity
Biological Process
GO:0006749 glutathione metabolic process
GO:0140977 cellular detoxification of acetone
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5m45, PDBe:5m45, PDBj:5m45
PDBsum5m45
PubMed28775283
UniProtQ8RM03|ACXB_XANP2 Acetone carboxylase alpha subunit (Gene Name=acxB)

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