Structure of PDB 5lzw Chain J

Receptor sequence

>5lzwJ (length=170) Species: 9986 (Oryctolagus cuniculus)

KENPMRELRIRKLCLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTV
RSFGIRRNEKIAVHCTVRGAKAEEILEKGLKVREYELRKNNFSDTGNFGF
GIQEHIDLGIKYDPSIGIYGLDFYVVLGRPGFSIADKKRRTGCIGAKHRI
SKEEAMRWFQQKYDGIILPG

3D structure

• PDB: 5lzw Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
• Chain: J
• Resolution: 3.53 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	J	T56 R64	T49 R57
BS02	rna	J	K19 C21 N23 C25 S51 A53 R54 S59 F60 N97 N98 S100 D101 T102 N104 G106 F107 G108 G127 D129 Y131 K145	K12 C14 N16 C18 S44 A46 R47 S52 F53 N90 N91 S93 D94 T95 N97 G99 F100 G101 G120 D122 Y124 K138
BS03	rna	J	M12 R13 Q46 T47 V49 C72 T73 R75 G138 S140 I141 D143 K144 R146 I151 G152 A153 K154 H155 R156	M5 R6 Q39 T40 V42 C65 T66 R68 G131 S133 I134 D136 K137 R139 I144 G145 A146 K147 H148 R149

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005634 nucleus
• GO:0005730 nucleolus
• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:5lzw, PDBe:5lzw, PDBj:5lzw
• PDBsum: 5lzw
• PubMed: 27863242
• UniProt: G1TUB8|RL11_RABIT Large ribosomal subunit protein uL5 (Gene Name=RPL11)