Structure of PDB 5iud Chain J

Receptor sequence
>5iudJ (length=861) Species: 9606 (Homo sapiens) [Search protein sequence]
EQVFHFYWLDAYEDQYNQPGVVFLFGKVWIESAETHVSCCVMVKNIERTL
YFLPREMKIDLNTGKETGTPISMKDVYEEFDEKIATKYKIMKFKSKPVEK
NYAFEIPDVPEKSEYLEVKYSAEMPQLPQDLKGETFSHVFGTNTSSLELF
LMNRKIKGPCWLEVKSPQLLNQPVSWCKVEAMALKPDLVNVIKDVSPPPL
VVMAFSMKTMQNAKNHQNEIIAMAALVHHSFALDKAAPKPPFQSHFCVVS
KPKDCIFPYAFKEVIEKKNVKVEVAATERTLLGFFLAKVHKIDPDIIVGH
NIYGFELEVLLQRINVCKAPHWSKIGRLKRSNMPKLFGERNATCGRMICD
VEISAKELIRCKSYHLSELVQQILKTERVVIPMENIQNMYSESSQLLYLL
EHTWKDAKFILQIMCELNVLPLALQITNIAGNIMSRTLMGGRSERNEFLL
LHAFYENNYIVPDKQIKAAYAGGLVLDPKVGFYDKFILLLDFNSLYPSII
QEFNICFTTVQRQIPELPDPSLEMGILPREIRKLVERRKQVKQLMKQQDL
NPDLILQYDIRQKALKLTANSMYGCLGFSYSRFYAKPLAALVTYKGREIL
MHTKEMVQKMNLEVIYGDTDSIMINTNSTNLEEVFKLGNKVKSEVNKLYK
LLEIDIDGVFKSLLLLKKKKYAALVVEPTSDGNYVTKQELKGLDIVRRDW
CDLAKDTGNFVIGQILSDQSRDTIVENIQKRLIEIGENVLNGSVPVSQFE
INKALTKDPQDYPDKKSLPHVHVALWINSQGGRKVKAGDTVSYVICQDGS
NLTASQRAYAPEQLQKQDNLTIDTQYYLAQQIHPVVARICEPIDGIDAVL
IATWLGLDPTQ
3D structure
PDB5iud Human DNA polymerase alpha in binary complex with a DNA:DNA template-primer.
ChainJ
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Interaction with ligand
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
Biological Process
GO:1902975 mitotic DNA replication initiation

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Molecular Function
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Biological Process
External links
PDB RCSB:5iud, PDBe:5iud, PDBj:5iud
PDBsum5iud
PubMed27032819
UniProtP09884|DPOLA_HUMAN DNA polymerase alpha catalytic subunit (Gene Name=POLA1)

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