Structure of PDB 4qd2 Chain J

Receptor sequence
>4qd2J (length=212) Species: 10090 (Mus musculus) [Search protein sequence]
WVIPPISCPENEKGEFPKNLVQIKSNRDKETKVFYSITGQGADKPPVGVF
IIERETGWLKVTQPLDREAIAKYILYSHAVSSNGEAVEDPMEIVITVTDQ
NDNRPEFTQEVFEGSVAEGAVPGTSVMKVSATDADDDVNTYNAAIAYTIV
SQDPELPHKNMFTVNRDTGVISVLTSGLDRESYPTYTLVVQAADLQGEGL
STTAKAVITVKD
3D structure
PDB4qd2 Molecular basis for disruption of E-cadherin adhesion by botulinum neurotoxin A complex.
ChainJ
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA J E11 D67 E69 D103 E10 D66 E68 D102
BS02 CA J E11 E69 D100 Q101 D103 D136 E10 E68 D99 Q100 D102 D135
BS03 CA J N102 N104 D134 D136 N143 D195 N101 N103 D133 D135 N142 D194
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0098609 cell-cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4qd2, PDBe:4qd2, PDBj:4qd2
PDBsum4qd2
PubMed24948737
UniProtP09803|CADH1_MOUSE Cadherin-1 (Gene Name=Cdh1)

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