Structure of PDB 3n7u Chain J

Receptor sequence
>3n7uJ (length=351) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
DSKKIVGVFYKANEYATKNPNFLGCVENALGIRDWLESQGHQYIVTDDKE
GPDCELEKHIPDLHVLISTPFHPAYVTAERIKKAKNLKLLLTAGIGSDHI
DLQAAAAAGLTVAEVTGSNVVSVAEDELMRILILMRNFVPGYNQVVKGEW
NVAGIAYRAYDLEGKTIGTVGAGRIGKLLLQRLKPFGCNLLYHDRLQMAP
ELEKETGAKFVEDLNEMLPKCDVIVINMPLTEKTRGMFNKELIGKLKKGV
LIVNNARGAIMERQAVVDAVESGHIGGYSGDVWDPQPAPKDHPWRYMPNQ
AMTPHTSGTTIDAQLRYAAGTKDMLERYFKGEDFPTENYIVKDGELAPQY
R
3D structure
PDB3n7u Structures of the apo and holo forms of NAD-dependent formate dehydrogenase from the higher-plant Arabidopsis Thaliana
ChainJ
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) N146 R284 D308 Q313 H332
Catalytic site (residue number reindexed from 1) N119 R257 D281 Q286 H305
Enzyme Commision number 1.17.1.9: formate dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD J I122 N146 V150 G200 R201 I202 D221 M255 P256 N282 R284 D308 H332 S334 G335 I95 N119 V123 G173 R174 I175 D194 M228 P229 N255 R257 D281 H305 S307 G308
BS02 AZI J P97 F98 I122 R284 H332 P70 F71 I95 R257 H305
Gene Ontology
Molecular Function
GO:0008863 formate dehydrogenase (NAD+) activity
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0051287 NAD binding
Biological Process
GO:0042183 formate catabolic process
Cellular Component
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0009507 chloroplast
GO:0009536 plastid
GO:0009579 thylakoid

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Molecular Function
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Cellular Component
External links
PDB RCSB:3n7u, PDBe:3n7u, PDBj:3n7u
PDBsum3n7u
PubMed
UniProtQ9S7E4|FDH_ARATH Formate dehydrogenase, chloroplastic/mitochondrial (Gene Name=FDH1)

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