Structure of PDB 3ias Chain J

Receptor sequence
>3iasJ (length=437) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
TGPILSGLDPRFERTLYAHVGKEGSWTLDYYLRHGGYETAKRVLKEKTPD
EVIEEVKRSGLRGRGGAGFPTGLKWSFMPKDDGKQHYLICNADESEPGSF
KDRYILEDVPHLLIEGMILAGYAIRATVGYIYVRGEYRRAADRLEQAIKE
ARARGYLGKNLFGTDFSFDLHVHRGAGAYICGEETALMNSLEGLRANPRL
KPPFPAQSGLWGKPTTINNVETLASVVPIMERGADWFAQMGTEQSKGMKL
YQISGPVKRPGVYELPMGTTFRELIYEWAGGPLEPIQAIIPGGSSTPPLP
FTEEVLDTPMSYEHLQAKGSMLGTGGVILIPERVSMVDAMWNLTRFYAHE
SCGKCTPCREGVAGFMVNLFAKIGTGQGEEKDVENLEALLPLIEGRSFCP
LADAAVWPVKGSLRHFKDQYLALAREKRPVPRPSLWR
3D structure
PDB3ias Structural basis for the mechanism of respiratory complex I
ChainJ
Resolution3.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SF4 J P199 S352 C353 G354 K355 C356 C359 F399 C400 L402 A403 P198 S351 C352 G353 K354 C355 C358 F398 C399 L401 A402
BS02 FMN J G64 G66 K75 N92 D94 Y180 G183 E184 N219 N220 T223 P401 G63 G65 K74 N91 D93 Y179 G182 E183 N218 N219 T222 P400
Gene Ontology
Molecular Function
GO:0008137 NADH dehydrogenase (ubiquinone) activity
GO:0010181 FMN binding
GO:0046872 metal ion binding
GO:0048038 quinone binding
GO:0051287 NAD binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0045271 respiratory chain complex I

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3ias, PDBe:3ias, PDBj:3ias
PDBsum3ias
PubMed19635800
UniProtQ56222|NQO1_THET8 NADH-quinone oxidoreductase subunit 1 (Gene Name=nqo1)

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