Structure of PDB 3ch1 Chain J

Receptor sequence

>3ch1J (length=272) Species: 10090 (Mus musculus) [Search protein sequence]

GPHSMRYFETAVSRPGEEPRYISVGYVDNKEFVRFDSDAENPRYEPRAPW
MEQEGPEYWERETQKAKGQEQWFRVSLRNLLGYYNQSAGGSHTLQQMSGC
DLGSDWRLLRGYLQFAYEGRDYIALNEDLKTWTAADMAAQITRRKWEQSG
AAEHYKAYLEGECVEWLHRYLKNGNLRTDSPKAHVTHHPRSKGEVTLRCW
ALGFYPADITLTWQLNGEELTQDMELVETRPAGDGTFQKWASVVVPLGKE
QNYTCRVYHEGLPEPLTLRWEP

3D structure

PDB

3ch1 Design of agonistic altered peptides for the robust induction of CTL directed towards H-2Db in complex with the melanoma-associated epitope gp100.

Chain

Resolution

2.3 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	J	Y7 E63 K66 Q70 W73 V76 S77 N80 Y84 Q97 S99 T143 K146 W147 S150 A152 H155 Y156 Y159 W167 Y171	Y7 E62 K65 Q69 W72 V75 S76 N79 Y83 Q96 S98 T142 K145 W146 S149 A151 H154 Y155 Y158 W166 Y170

External links

PDB	RCSB:3ch1, PDBe:3ch1, PDBj:3ch1
PDBsum	3ch1
PubMed	19789338
UniProt	P01899\|HA11_MOUSE H-2 class I histocompatibility antigen, D-B alpha chain (Gene Name=H2-D1)

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