Structure of PDB 3cch Chain J

Receptor sequence

>3cchJ (length=272) Species: 10090 (Mus musculus) [Search protein sequence]

GPHSMRYFETAVSRPGLEEPRYISVGYVDNKEFVRFDSDAENPRYEPRAP
WMEQEGPEYWERETQKAKGQEQWFRVSLRNLLGYYNQSAGGSHTLQQMSG
CDLGSDWRLLRGYLQFAYEGRDYIALNEDLKTWTAADMAAQITRRKWEQS
GAAEHYKAYLEGECVEWLHRYLKNGLRTDSPKAHVTHHPRSKGEVTLRCW
ALGFYPADITLTWQLNGEELTQDMELVETRPAGDGTFQKWASVVVPLGKE
QNYTCRVYHEGLPEPLTLRWEP

3D structure

PDB

3cch Design of agonistic altered peptides for the robust induction of CTL directed towards H-2Db in complex with the melanoma-associated epitope gp100.

Chain

Resolution

2.6 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	J	M5 Y7 E63 K66 Q70 W73 S77 Y84 Q97 T143 K146 W147 S150 A152 H155 Y156 Y159 W167 Y171	M5 Y7 E63 K66 Q70 W73 S77 Y84 Q97 T143 K146 W147 S150 A152 H155 Y156 Y159 W167 Y171

External links

PDB	RCSB:3cch, PDBe:3cch, PDBj:3cch
PDBsum	3cch
PubMed	19789338
UniProt	P01899\|HA11_MOUSE H-2 class I histocompatibility antigen, D-B alpha chain (Gene Name=H2-D1)

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