Structure of PDB 8ppl Chain Ip

Receptor sequence
>8pplIp (length=105) Species: 9606 (Homo sapiens) [Search protein sequence]
SFDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKK
LVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLVEIGLAKDDQL
KVHGF
3D structure
PDB8ppl Universal features of Nsp1-mediated translational shutdown by coronaviruses.
ChainIp
Resolution2.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna Ip R38 K42 K61 K64 K65 A68 C69 N70 T72 Q84 Q86 R30 K34 K53 K56 K57 A60 C61 N62 T64 Q76 Q78
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003743 translation initiation factor activity
GO:0005515 protein binding
GO:0008135 translation factor activity, RNA binding
GO:0043024 ribosomal small subunit binding
Biological Process
GO:0006412 translation
GO:0006413 translational initiation
GO:0006446 regulation of translational initiation
GO:1905746 positive regulation of mRNA cis splicing, via spliceosome
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016282 eukaryotic 43S preinitiation complex
GO:0033290 eukaryotic 48S preinitiation complex
GO:0043614 multi-eIF complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ppl, PDBe:8ppl, PDBj:8ppl
PDBsum8ppl
PubMed37802027
UniProtP41567|EIF1_HUMAN Eukaryotic translation initiation factor 1 (Gene Name=EIF1)

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