Structure of PDB 7b6c Chain III

Receptor sequence
>7b6cIII (length=272) Species: 1891762 (Betapolyomavirus hominis) [Search protein sequence]
VDGQPMYGMESQVEEVRVFDTGVDAITEVECFLNPEMGDPDENLRGFSLK
LSAENDFSSDSPERKMLPCYSTARIPLPNLNELLMWEAVTVQTEVIGITS
MLNLHAGSQKVHEHGGGKPIQGSNFHFFAVGGEPLEMQGVLMNYRSKYPD
GTITPKNPTAQSQVMNTDHKAYLDKNNAYPVECWVPDPSRNENARYFGTF
TGGENVPPVLHVTNTATTVLLDEQGVGPLCKADSLYVSAADICGLFTNSS
GTQQWRGLARYFKIRLRKRSVK
3D structure
PDB7b6c Discovery of novel druggable pockets on polyomavirus VP1 through crystallographic fragment-based screening to develop capsid assembly inhibitors.
ChainIII
Resolution2.484 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA III R35 E48 R17 E30
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
Cellular Component
GO:0019028 viral capsid

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Molecular Function
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Cellular Component
External links
PDB RCSB:7b6c, PDBe:7b6c, PDBj:7b6c
PDBsum7b6c
PubMed35974998
UniProtP03088|VP1_POVBK Major capsid protein VP1

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