Structure of PDB 8g2z Chain IE

Receptor sequence
>8g2zIE (length=432) Species: 452467 (Tetrahymena thermophila CU428) [Search protein sequence]
MREVISIHVGQGGIQVGNACWELFCLEHGIQPDGQMPSDDAFNTFFSETG
AGKHVPRAVFLDLEPTVIDEVRTGTYRQLFHPEQLISGKEDAANNFARGH
YTIGKEIVDLCLDRIRKLADNCTGLQGFLVFNSVGGGTGSGLGSLLLERL
SVDYGKKSKLGFTIYPSPQVSTAVVEPYNSILSTHSLLEHTDVAVMLDNE
AIYDICRRNLDIERPTYTNLNRLIAQVISSLTASLRFDGALNVDITEFQT
NLVPYPRIHFMLSSYAPIISAEKAYHEQLSVAEITNSAFEPANMMAKCDP
RHGKYMACSMMYRGDVVPKDVNASIATIKTKRTIQFVDWCPTGFKVGINY
QPPTVVPGGDLAKVMRAVCMISNSTAIAEVFSRLDHKFDLMYAKRAFVHW
YVGEGMEEGEFSEAREDLAALEKDYEEVGIET
3D structure
PDB8g2z Native doublet microtubules from Tetrahymena thermophila reveal the importance of outer junction proteins.
ChainIE
Resolution4.1 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.6.5.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GTP IE Q11 G12 Q15 D98 N101 S140 G143 T145 I171 T179 Y224 Q11 G12 Q15 D91 N94 S133 G136 T138 I164 T172 Y217
BS02 MG IE Q11 D98 Q11 D91
Gene Ontology
Molecular Function
GO:0005200 structural constituent of cytoskeleton
GO:0005525 GTP binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0000278 mitotic cell cycle
GO:0007017 microtubule-based process
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005874 microtubule

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8g2z, PDBe:8g2z, PDBj:8g2z
PDBsum8g2z
PubMed37061538
UniProtP41351|TBA_TETTH Tubulin alpha chain

[Back to BioLiP]