Structure of PDB 6hcf Chain I3

Receptor sequence

>6hcfI3 (length=205) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence]

GRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDEFPLCGH
MVSDEYEQLSSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINK
MLQTGMRGAFGKPQGTVARVHIGQVIMSIRTKLQNKEHVVEALRRAKFKF
PGRQKIHISKKWGFTKFNADEFEDMVAEKRLIPDGCGVKYIPNRGPLDKW
RALHS

3D structure

PDB

6hcf ZNF598 Is a Quality Control Sensor of Collided Ribosomes.

Chain

Resolution

3.9 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	I3	R3 R4 R7 C8 K13 N14 K15 P16 Y17 F22 K39 K40 E63 H92 F94 R98 N100 M115 R116 G117 A118 F119 Q133 R154 F157 K158 R162 D193	R2 R3 R6 C7 K12 N13 K14 P15 Y16 F21 K38 K39 E62 H91 F93 R97 N99 M106 R107 G108 A109 F110 Q124 R145 F148 K149 R153 D184
BS02	rna	I3	Y11 E56 R203 G204 P205 L206	Y10 E55 R194 G195 P196 L197

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0000027	ribosomal large subunit assembly
GO:0006412	translation
GO:0006417	regulation of translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:6hcf, PDBe:6hcf, PDBj:6hcf
PDBsum	6hcf
PubMed	30293783
UniProt	B7NZQ2\|RL10_RABIT Large ribosomal subunit protein uL16 (Gene Name=RPL10)

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