Structure of PDB 8yha Chain I

Receptor sequence

>8yhaI (length=266) Species: 1852835 (Candidatus Cloacimonetes bacterium ADurb.Bin088) [Search protein sequence]

MLIEIHMIQNHSPANLNRDDLGAPKTCYFGGVLRSRISSQCIKRSIRTSN
DFKALLLAPDIALCGRTVEAALQVAHAISTHIARPEIDYFVAADDVPGED
AGAGHIGESMFASACFYKYFSIDWEQLVKNLKGDTNLAAHTVGAFLLAAA
KTNPSGKQNSFAAHNYPDGILVEFKNSPISYANAFVRPVSVVKESDLVEQ
SIGQLSNYVNDIRLGYYDEQSPVIGFWFSPNNRYPLGYKHSKLASRNIGN
LNELVGAVLDYIGGFK

3D structure

PDB

8yha Mechanisms for HNH-mediated target DNA cleavage in type I CRISPR-Cas systems

Chain

Resolution

3.4 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	I	R18 K25 Q40 K43 R47 G146 E168 Y188 F189 V190 A192 Q225 K256	R18 K25 Q40 K43 R47 G65 E69 Y89 F90 V91 A93 Q126 K157
BS02	dna	I	A200 A202 H204 I205	A101 A103 H105 I106

External links

PDB	RCSB:8yha, PDBe:8yha, PDBj:8yha
PDBsum	8yha
PubMed	39047725
UniProt	A0A1V6F8B5

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