Structure of PDB 8yeo Chain I

Receptor sequence

>8yeoI (length=324) Species: 2053611 (Selenomonas sp.) [Search protein sequence]

LKSRPENLSFARCLNTTEAKFWQTDFLKRHTFKLPLLITDKAVLASKGHE
MPPDKLEKEIMDPNPQKSQSCTLSTECDTLRIDFGIKVLPVKESMYSCSD
YNYRTAIYQKIDEYIAEDGFLTLAKRYVNNIANARFLWRNRKGAEIIETI
VTIEDKEYPSFNSKSFNLDTFVEDNATINEIAQQIADTFAGKREYLNIYV
TCFVKIGCAMEVYPSQEMTFDDDDKGKKLFKFEGSAGMHSQKINNALRTI
DTWYPDYTTYEFPIPVENYGAARSIGIPFRPDTKSFYKLIDRMILKNEDL
PIEDKHYVMAILIRGGMFSKKQEK

3D structure

PDB

8yeo Mechanisms for HNH-mediated target DNA cleavage in type I CRISPR-Cas systems

Chain

Resolution

3.44 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	I	S20 F21 A22 R23 L55 A56 W149 R150 Q227 M229 H250 K253 N256 R259 R284 M328	S9 F10 A11 R12 L44 A45 W138 R139 Q216 M218 H239 K242 N245 R248 R273 M317
BS02	rna	I	H60 P74 N75 P76 Q77 F231	H49 P63 N64 P65 Q66 F220

External links

PDB	RCSB:8yeo, PDBe:8yeo, PDBj:8yeo
PDBsum	8yeo
PubMed	39047725

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