Structure of PDB 8ttw Chain I

Receptor sequence
>8ttwI (length=451) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence]
ENLWVTVYYGVPVWKDAETTLFCASDAKAYETEKHNVWATHACVPTDPNP
QEIHLENVTEEFNMWKNNMVEQMHTDIISLWDQSLKPCVKLTPLCVTLQC
TNVTNNITDDMRGELKNCSFNMTTELRDKKQKVYSLFYRLDVVQINNKEY
RLINCNTSAITQACPKVSFEPIPIHYCAPAGFAILKCKDKKFNGTGPCPS
VSTVQCTHGIKPVVSTQLLLNGSLAEEEVMIRSENITNNAKNILVQFNTP
VQINCTRPNNNTRKSIRIGPGQAFYATGDIIGDIRQAHCNVSKATWNETL
GKVVKQLRKHFGNNTIIRFANSSGGDLEVTTHSFNCGGEFFYCNTSGLFN
STWISNNDSITLPCRIKQIINMWQRIGQAMYAPPIQGVIRCVSNITGLIL
TRDGGSTNSTTETFRPGGGDMRDNWRSELYKYKVVKIEPLGVAPTRCKRR
V
3D structure
PDB8ttw Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir.
ChainI
Resolution2.96 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MAN I K65 E211 K34 E170
BS02 83J I I109 W112 D113 V255 S375 F382 I424 M426 W427 A433 I78 W81 D82 V214 S333 F340 I370 M372 W373 A379
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:8ttw, PDBe:8ttw, PDBj:8ttw
PDBsum8ttw
PubMed37872202
UniProtQ2N0S6

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