Structure of PDB 8rw1 Chain I

Receptor sequence

>8rw1I (length=188) Species: 284590 (Kluyveromyces lactis NRRL Y-1140) [Search protein sequence]

GISRDSRHKRAATGAKRAQFRKKRKFELGRQAANTKIGTKRIHPVRTRGG
NQKFRALRIETGNFSWASEGVARKTRITGVVYHPSNNELVRTNTLTKAAI
VQIDATPFRQWYESHYGQSLGKTSKNTERKWAARAAEAKIEHAVDSQFGA
GRLYAAISSRPGQSGRCDGYILEGEELAFYLRRLTAKK

3D structure

PDB

8rw1 Structural basis of AUC codon discrimination during translation initiation in yeast.

Chain

Resolution

3.35 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	I	G2 R5 H9 K10 R11 T14 A16 F21 R22 K23 K24 R25 K26 F27 L29 G30 R31 Q32 A33 A34 K41 R42 I43 H44 R47 T48 R49 G50 N52 K54 R56 L58 R59 N64 S66 V72 A73 R74 K75 S86 T97 K98 S137 N139 T140 R142 S171 S172 R173 G175 Q176 S177 R179 D181	G1 R4 H8 K9 R10 T13 A15 F20 R21 K22 K23 R24 K25 F26 L28 G29 R30 Q31 A32 A33 K40 R41 I42 H43 R46 T47 R48 G49 N51 K53 R55 L57 R58 N63 S65 V71 A72 R73 K74 S85 T96 K97 S124 N126 T127 R129 S158 S159 R160 G162 Q163 S164 R166 D168

External links

PDB	RCSB:8rw1, PDBe:8rw1, PDBj:8rw1
PDBsum	8rw1
PubMed	39193907
UniProt	Q6CMG3

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