Structure of PDB 8jay Chain I

Receptor sequence
>8jayI (length=448) Species: 1393122 (Thermoflavifilum thermophilum) [Search protein sequence]
MKELIYIEEPSILFAHGQKCTDPRDGLALFGPLNQIYGIKSGVVGTQKGL
QIFKSYLDKIQKPIYNHNNITRPMFPGFEAVFGCKWESQNIVFKEITDEE
IRRYLFNASTHKRTYDLVTLFNDKIITANKNDEERVDVWFVIVPAQFHDQ
LKARLLEHTIPTQILRESTLAWRDFKNTFGAPIRDFSKIEGHLAWTISTA
AYYKAGGKPWKLGDIRPGVCYLGLVYKKIEKSKNPQNACCAAQMFLDNGD
GTVFKGEVGPWYNPEKGEYHLKPKEAKALLTQALESYKEQNKSYPKEVFI
HARTRFNDEEWNAFNEVTPKNTNLVGVTITKSKPLKLYKTEGAFPIMRGN
AYIVDEKKAFLWTLGFVPKLQSTLSMEVPNPIFIEINKGEAEIQQVLKDI
LALTKLNYNACIYADGEPVTLRFANKIGEILTASTEIKTPPLAFKYYI
3D structure
PDB8jay Auto-inhibition and activation of a short Argonaute-associated TIR-APAZ defense system.
ChainI
Resolution4.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna I H207 I223 L224 R225 T228 F245 I248 K390 L423 N468 D474 I507 H148 I164 L165 R166 T169 F186 I189 K331 L364 N409 D415 I448
BS02 dna I R72 K286 K287 Y328 R362 T363 R364 R72 K227 K228 Y269 R303 T304 R305
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding

View graph for
Molecular Function
External links
PDB RCSB:8jay, PDBe:8jay, PDBj:8jay
PDBsum8jay
PubMed37932527
UniProtA0A1I7NFD7

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