Structure of PDB 8ir3 Chain I

Receptor sequence
>8ir3I (length=190) Species: 9606 (Homo sapiens) [Search protein sequence]
MKTILSNQTVDIPENVDITLKGRTVIVKGPRGTLRRDFNHINVELSLLGK
KKKRLRVDKWWGNRKELATVRTICSHVQNMIKGVTLGFRYKMRSVYAHFP
INVVIQENGSLVEIRNFLGEKYIRRVRMRPGVACSVSQAQKDELILEGND
IELVSNSAALIQQATTVKNKDIRKFLDGIYVSEKGTVQQA
3D structure
PDB8ir3 Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles.
ChainI
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna I M1 R23 H40 V43 K51 K52 K59 W60 R64 K65 A68 R71 T72 S75 H76 N79 H98 F99 E120 K121 Y122 S155 Q163 K170 D171 R173 K174 F175 M1 R23 H40 V43 K51 K52 K59 W60 R64 K65 A68 R71 T72 S75 H76 N79 H98 F99 E120 K121 Y122 S155 Q163 K170 D171 R173 K174 F175
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0005925 focal adhesion
GO:0016020 membrane
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8ir3, PDBe:8ir3, PDBj:8ir3
PDBsum8ir3
PubMed37491604
UniProtP32969|RL9_HUMAN Large ribosomal subunit protein uL6 (Gene Name=RPL9)

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