Structure of PDB 8ip0 Chain I

Receptor sequence

>8ip0I (length=299) Species: 1147 (Synechocystis sp. PCC 6714) [Search protein sequence]

NLNLFATILTYPAPASNYRGESEENRSVIQKILKDGQKYAIISPESMRNA
LREMLIELGQPNNRTRLHSEDQLAVEFKEYPNPDKFADDFLFGYMVAQTN
DAKEMKKLNRPAKRDSIFRCNMAVAVNPYKYDTVFYQSPLNAGDSAWKNS
TSSALLHREVTHTAFQYPFALAGKDCAAKPEWVKALLQAIAELNGVAGGH
ARAYYEFAPRSVVARLTPKLVAGYQTYGFDAEGNWLELSRLTATDSDNLD
LPANEFWLGGELVRKMDQEQKAQLEAMGAHLYANPEKLFADLADSFLGV

3D structure

PDB

8ip0 Cryo-EM structure of type I-B Cascade bound to a PAM-containing dsDNA target at 3.6 angstrom resolution.

Chain

Resolution

3.6 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	I	Y20 E23 E47 S48 R50 N51 R54 R66 R68 Y96 M97 R116 F137 Y138 Q139 S140 G200 G201 R204	Y18 E21 E45 S46 R48 N49 R52 R64 R66 Y94 M95 R114 F135 Y136 Q137 S138 G198 G199 R202
BS02	dna	I	E26 D73 T101 S152 S155 A156 L157 L158	E24 D71 T99 S150 S153 A154 L155 L156

External links

PDB	RCSB:8ip0, PDBe:8ip0, PDBj:8ip0
PDBsum	8ip0
PubMed	38750051
UniProt	A0A068N458

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