Structure of PDB 8iah Chain I

Receptor sequence
>8iahI (length=373) Species: 9823 (Sus scrofa) [Search protein sequence]
DDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDS
YVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHP
VLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIV
MDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTT
TAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGN
ERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGG
TTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTF
QQMWISKQEYDESGPSIVHRKCF
3D structure
PDB8iah Structural basis of membrane skeleton organization in red blood cells.
ChainI
Resolution3.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP I G13 S14 G15 G156 D157 K213 E214 G302 Y306 K336 G11 S12 G13 G154 D155 K211 E212 G300 Y304 K334
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0019901 protein kinase binding
GO:0098973 structural constituent of postsynaptic actin cytoskeleton
Biological Process
GO:0007409 axonogenesis
GO:0048870 cell motility
GO:0098974 postsynaptic actin cytoskeleton organization
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005884 actin filament
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0015629 actin cytoskeleton
GO:0016020 membrane
GO:0030424 axon
GO:0032991 protein-containing complex
GO:0035267 NuA4 histone acetyltransferase complex
GO:0045202 synapse
GO:0097433 dense body

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8iah, PDBe:8iah, PDBj:8iah
PDBsum8iah
PubMed37044097
UniProtQ6QAQ1|ACTB_PIG Actin, cytoplasmic 1 (Gene Name=ACTB)

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