Structure of PDB 8gsv Chain I

Receptor sequence
>8gsvI (length=155) Species: 9606 (Homo sapiens) [Search protein sequence]
MSEEQVAQDTEEVFRSYVFYRHQQEQEAADPEMVTLPLQPSSTMGQVGRQ
LAIIGDDINRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFESGINWGR
VVALLGFGYRLALHVYQHGLTGFLGQVTRFVVDFMLHHSIARWIAQRGGW
VAALN
3D structure
PDB8gsv Structural basis for proapoptotic activation of Bak by the noncanonical BH3-only protein Pxt1.
ChainI
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide I I85 Y89 F93 M96 K113 I114 S117 L118 S121 N124 G126 R127 A130 F134 I58 Y62 F66 M69 K86 I87 S90 L91 S94 N97 G99 R100 A103 F107
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:8gsv, PDBe:8gsv, PDBj:8gsv
PDBsum8gsv
PubMed37315086
UniProtQ16611|BAK_HUMAN Bcl-2 homologous antagonist/killer (Gene Name=BAK1)

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