Structure of PDB 8g6e Chain I

Receptor sequence
>8g6eI (length=221) Species: 5843 (Plasmodium falciparum NF54) [Search protein sequence]
TTICGLVCQNAVILGADTRATEGPIVADKNCSKLHYISKNIWCAGAGVAG
DLEHTTLWLQHNVELHRLNTNTQPRVSMCVSRLTQELFKYQGYKVCAIVL
GGVDVNGPQLYGIHPHGSSCLLPFTALGSGSLNAMAVLEAKYRDNMTIEE
GKNLVCEAICAGIFNDLGSGGNVDICVITKDSYQHIRPYKEPNMRLYHLP
HPTIYPKGTTPILSEKIEYIK
3D structure
PDB8g6e Structures revealing mechanisms of resistance and collateral sensitivity of Plasmodium proteasome inhibitors
ChainI
Resolution2.18 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.25.1: proteasome endopeptidase complex.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 YRE I A20 T21 E22 G47 V48 A49 L52 A20 T21 E22 G47 V48 A49 L52
Gene Ontology
Molecular Function
GO:0004298 threonine-type endopeptidase activity
Biological Process
GO:0051603 proteolysis involved in protein catabolic process
Cellular Component
GO:0005839 proteasome core complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8g6e, PDBe:8g6e, PDBj:8g6e
PDBsum8g6e
PubMed38097652
UniProtW7K1J4

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