Structure of PDB 8fyw Chain I

Receptor sequence
>8fywI (length=519) Species: 10804 (adeno-associated virus 2) [Search protein sequence]
GADGVGNSSGNWHCDSTWMGDRVITTSTRTWALPTYNNHLYKQISSQSGA
SNDNHYFGYSTPWGYFDFNRFHCHFSPRDWQRLINNNWGFRPKRLNFKLF
NIQVKEVTQNDGTTTIANNLTSTVQVFTDSEYQLPYVLGSAHQGCLPPFP
ADVFMVPQYGYLTLNNGSQAVGRSSFYCLEYFPSQMLRTGNNFTFSYTFE
DVPFHSSYAHSQSLDRLMNPLIDQYLYYLSRTNTPSGTTTQSRLQFSQAG
ASDIRDQSRNWLPGPCYRQQRVSKTSADNNNSEYSWTGATKYHLNGRDSL
VNPGPAMASHKDDEEKFFPQSGVLIFGKQGSEKTNVDIEKVMITDEEEIR
TTNPVATEQYGSVSTNLQRGNRQAATADVNTQGVLPGMVWQDRDVYLQGP
IWAKIPHTDGHFHPSPLMGGFGLKHPPPQILIKNTPVPANPSTTFSAAKF
ASFITQYSTGQVSVEIEWELQKENSKRWNPEIQYTSNYNKSVNVDFTVDT
NGVYSEPRPIGTRYLTRNL
3D structure
PDB8fyw Cryo-EM Structure of genome containing AAV2
ChainI
Resolution2.84 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DA I H629 P630 S631 G638 H413 P414 S415 G422
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
Biological Process
GO:0019062 virion attachment to host cell
GO:0046718 symbiont entry into host cell
GO:0075512 clathrin-dependent endocytosis of virus by host cell
GO:0140267 symbiont entry into host cell via permeabilization of host membrane
Cellular Component
GO:0019028 viral capsid
GO:0039615 T=1 icosahedral viral capsid
GO:0042025 host cell nucleus
GO:0044196 host cell nucleolus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8fyw, PDBe:8fyw, PDBj:8fyw
PDBsum8fyw
PubMed
UniProtP03135|CAPSD_AAV2S Capsid protein VP1 (Gene Name=VP1)

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