Structure of PDB 8dck Chain I

Receptor sequence
>8dckI (length=691) Species: 199310 (Escherichia coli CFT073) [Search protein sequence]
DYGLYALEILAQYHNVSVNPEEIKHRFDTDGTGLGLTSWLLAAKSLELKV
KQVKKTIDRLNFISLPALVWREDGRHFILTKVSKEANRYLIFDLEQRNPR
VLEQSEFEALYQGHIILIASRSSLAKFDFTWFIPAIIKYRKIFIETLVVS
VFLQLFALITPLFFQVVMDKVLVHRGFSTLNVITVALSVVVVFEIILSGL
RTYIFAHSTSRIDVELGAKLFRHLLALPISYFESRRVGDTVARVRELDQI
RNFLTGQALTSVLDLLFSFIFFAVMWYYSPKLTLVILFSLPCYAAWSVFI
SPILRRRLDDKFSRNADNQSFLVESVTAINTIKAMAVSPQMTNIWDKQLA
GYVAAGFKVTVLATIGQQGIQLIQKTVMIINLWLGAHLVISGDLSIGQLI
AFNMLAGQIVAPVIRLAQIWQDFQQVGISVTRLGDVLNSPTESYHGKLAL
PEINGNITFRNIRFRYKPDSPVILDNINLSIKQGEVIGIVGRSGSGKSTL
TKLIQRFYIPENGQVLIDGHDLALADPNWLRRQVGVVLQDNVLLNRSIID
NISLANPGMSVEKVIYAAKLAGAHDFISELREGYNTIVGEQGAGLSGGQR
QRIAIARALVNNPKILIFDQATSALDYESEHIIMRNMHKICKGRTVIIIA
HRLSTVKNADRIIVMEKGKIVEQGKHKELLSEPESLYSYLY
3D structure
PDB8dck The hemolysin A secretion system is a multi-engine pump containing three ABC transporters.
ChainI
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP I Y477 I484 S504 G505 S506 G507 K508 S509 T510 Q550 Q631 H662 Y466 I473 S493 G494 S495 G496 K497 S498 T499 Q539 Q620 H651
BS02 MG I S509 Q550 S498 Q539
BS03 ATP I A604 G605 S607 G609 Q610 A593 G594 S596 G598 Q599
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0008233 peptidase activity
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0034040 ATPase-coupled lipid transmembrane transporter activity
GO:0140359 ABC-type transporter activity
Biological Process
GO:0006508 proteolysis
GO:0006869 lipid transport
GO:0030253 protein secretion by the type I secretion system
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0030256 type I protein secretion system complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8dck, PDBe:8dck, PDBj:8dck
PDBsum8dck
PubMed36055198
UniProtQ8FDZ8|HLYB_ECOL6 Alpha-hemolysin translocation ATP-binding protein HlyB (Gene Name=hlyB)

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