Structure of PDB 8b9z Chain I

Receptor sequence
>8b9zI (length=186) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
EPKDIVEVPKGYVYVNNKELSMEFADITDRAASTMFFGELLRGFAVTLAH
IFKEPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAICPAQ
AITIEAEERADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFS
TETHEELLYNKEKLLCNGDKWESEIASNLQADHLYR
3D structure
PDB8b9z Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster.
ChainI
Resolution3.28 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.1.1.2: NADH:ubiquinone reductase (H(+)-translocating).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SF4 I H106 C128 P129 C157 I158 Y159 C160 G161 F162 C163 E174 H75 C97 P98 C126 I127 Y128 C129 G130 F131 C132 E143
BS02 SF4 I C118 I119 A120 C121 K122 C124 Y150 C167 A171 I172 C87 I88 A89 C90 K91 C93 Y119 C136 A140 I141
Gene Ontology
Molecular Function
GO:0016651 oxidoreductase activity, acting on NAD(P)H
GO:0051539 4 iron, 4 sulfur cluster binding
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:8b9z, PDBe:8b9z, PDBj:8b9z
PDBsum8b9z
PubMed36622099
UniProtQ9VF27|NDUS8_DROME NADH dehydrogenase (ubiquinone) 23 kDa subunit (Gene Name=ND-23)

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