Structure of PDB 7qwq Chain I

Receptor sequence

>7qwqI (length=204) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence]

GRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDEFPLCGH
MVSDEYEQLSSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINK
MLTGMRGAFGKPQGTVARVHIGQVIMSIRTKLQNKEHVVEALRRAKFKFP
GRQKIHISKKWGFTKFNADEFEDMVAEKRLIPDGCGVKYIPNRGPLDKWR
ALHS

3D structure

PDB

7qwq Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting.

Chain

Resolution

2.83 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	I	R3 R4 A6 C8 Y9 K13 N14 K15 P16 Y17 F22 R24 D35 K40 E63 A64 R90 H92 F94 R98 N100 G114 M115 R116 A118 F119 Q133 R154 F157 K158 P160 D193 G194 K198	R2 R3 A5 C7 Y8 K12 N13 K14 P15 Y16 F21 R23 D34 K39 E62 A63 R89 H91 F93 R97 N99 G104 M105 R106 A108 F109 Q123 R144 F147 K148 P150 D183 G184 K188
BS02	rna	I	Y11 E56 Y57 Y199 N202 R203 G204 P205 L206	Y10 E55 Y56 Y189 N192 R193 G194 P195 L196

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0000027	ribosomal large subunit assembly
GO:0006412	translation
GO:0006417	regulation of translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:7qwq, PDBe:7qwq, PDBj:7qwq
PDBsum	7qwq
PubMed	35201867
UniProt	B7NZQ2\|RL10_RABIT Large ribosomal subunit protein uL16 (Gene Name=RPL10)

[Back to BioLiP]