Structure of PDB 7p7c Chain I

Receptor sequence
>7p7cI (length=180) Species: 469008 (Escherichia coli BL21(DE3)) [Search protein sequence]
MTLKELLVGFGTQVRSIWMIGLHAFAKRETRMYPEEPVYLPPRYRGRIVL
TRDPDGEERCVACNLCAVACPVGCISLQKAETKDGRWYPEFFRINFSRCI
FCGLCEEACPTTAIQLTPDFEMGEYKRQDLVYEKEDLLISGPGKYPEYNF
YRMAGMAIDGKDKGEAENEAKPIDVKSLLP
3D structure
PDB7p7c A universal coupling mechanism of respiratory complex I.
ChainI
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SF4 I I48 C70 C74 I75 C99 I100 F101 C102 G103 C105 I48 C70 C74 I75 C99 I100 F101 C102 G103 C105
BS02 SF4 I C60 V61 A62 C63 N64 C66 F92 C109 P110 T111 I114 C60 V61 A62 C63 N64 C66 F92 C109 P110 T111 I114
Gene Ontology
Molecular Function
GO:0003954 NADH dehydrogenase activity
GO:0005506 iron ion binding
GO:0016651 oxidoreductase activity, acting on NAD(P)H
GO:0046872 metal ion binding
GO:0048038 quinone binding
GO:0050136 NADH:ubiquinone reductase (non-electrogenic) activity
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0009060 aerobic respiration
GO:0022904 respiratory electron transport chain
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0030964 NADH dehydrogenase complex
GO:0045271 respiratory chain complex I

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Cellular Component
External links
PDB RCSB:7p7c, PDBe:7p7c, PDBj:7p7c
PDBsum7p7c
PubMed36104567
UniProtP0AFD6|NUOI_ECOLI NADH-quinone oxidoreductase subunit I (Gene Name=nuoI)

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