Structure of PDB 7nfx Chain I

Receptor sequence

>7nfxI (length=204) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence]

GRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDEFPLCGH
MVSDEYEQLSSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINK
MLTGMRGAFGKPQGTVARVHIGQVIMSIRTKLQNKEHVVEALRRAKFKFP
GRQKIHISKKWGFTKFNADEFEDMVAEKRLIPDGCGVKYIPNRGPLDKWR
ALHS

3D structure

PDB

7nfx Receptor compaction and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER.

Chain

Resolution

3.2 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	I	R3 R4 A6 R7 C8 N14 K15 P16 Y17 F22 R24 K30 F34 D35 K39 K40 S61 E63 A64 A67 K74 R88 R90 H92 F94 R98 M115 R116 A118 F119 G120 Q133 F157 K158 P160 D193 G194 C195 K198	R2 R3 A5 R6 C7 N13 K14 P15 Y16 F21 R23 K29 F33 D34 K38 K39 S60 E62 A63 A66 K73 R87 R89 H91 F93 R97 M105 R106 A108 F109 G110 Q123 F147 K148 P150 D183 G184 C185 K188
BS02	rna	I	R10 Y11 Y57 I131 Y199 N202 R203 G204 P205 L206 W209	R9 Y10 Y56 I121 Y189 N192 R193 G194 P195 L196 W199

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0000027	ribosomal large subunit assembly
GO:0006412	translation
GO:0006417	regulation of translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:7nfx, PDBe:7nfx, PDBj:7nfx
PDBsum	7nfx
PubMed	34020957
UniProt	B7NZQ2\|RL10_RABIT Large ribosomal subunit protein uL16 (Gene Name=RPL10)

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