Structure of PDB 7lbm Chain I

Receptor sequence
>7lbmI (length=116) Species: 9606 (Homo sapiens) [Search protein sequence]
GFVGIRFCQECNNMLYPKEDKENRILLYACRNCDYQQEADNSCIYVNKIT
HEVDELTQIIADVSQDPTLPRTEDHPCQKCGHKEAVFFQSHSARAEDAMR
LYYVCTAPHCGHRWTE
3D structure
PDB7lbm Structure of the human Mediator-bound transcription preinitiation complex.
ChainI
Resolution4.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN I C17 E19 C20 C8 E10 C11
BS02 ZN I C86 C114 C119 C77 C105 C110
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0001193 maintenance of transcriptional fidelity during transcription elongation by RNA polymerase II
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0006351 DNA-templated transcription
GO:0006366 transcription by RNA polymerase II
GO:0006367 transcription initiation at RNA polymerase II promoter
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005665 RNA polymerase II, core complex
GO:0005730 nucleolus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7lbm, PDBe:7lbm, PDBj:7lbm
PDBsum7lbm
PubMed33707221
UniProtP36954|RPB9_HUMAN DNA-directed RNA polymerase II subunit RPB9 (Gene Name=POLR2I)

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