Structure of PDB 7k36 Chain I

Receptor sequence
>7k36I (length=599) Species: 9606 (Homo sapiens) [Search protein sequence]
EFEYADTDKWAAELSELYSYTEGPEFLMNRKCFEEDFRIHVTDKKWTELD
TNQHRTHAMRLLDGLEVTAREKRLKVARAILYVAQGTSSEAEVQSWMRYN
IFLLLEVGTFNALVELLNMEIDNISLADSTDLRVLLNIMYLIVETVHQEC
EEWRTMRQTFRAELGSPLYNNEPFAIMLFGMVTKFCSGHAPHFPMKKVLL
LLWKTVLCTLGGFEELQSMKAEKRSILGLPPLPEDSIKVIRNMRAAGLPW
APKVREKDIEMFLESSRSKFIGYTLGSDTNTVVGLPRPIHESIKTLKQHK
YTSIAEVQAQMEEEYLRSPLSGGEEEVEQVPAETLYQGLLPSLPQYMIAL
LKILLAAAPTINILADVLPTVLQSMKLGVDVNRHKEVIVKAISAVLLLLL
KHFKLNHVYQFEYMAQHLVFANCIPLILKFFNQNIMSYITAKNSISQFCW
RNLFSCINLLRILNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLY
VLKLLKVQTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDWDFQAE
ECALRANIERFNARRYDRAHSNPDFLPVDNCLQSVLGFQMNYDLWLERE
3D structure
PDB7k36 Cryo-EM structure of the Hippo signaling integrator human STRIPAK.
ChainI
Resolution3.3 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IHP I K308 K427 Y475 S477 K587 K590 K677 K680 Y712 K715 R744 R746 K220 K253 Y301 S303 K401 K404 K465 K468 Y500 K503 R532 R534
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0019901 protein kinase binding
GO:0030674 protein-macromolecule adaptor activity
GO:0031267 small GTPase binding
Biological Process
GO:0007010 cytoskeleton organization
GO:0022604 regulation of cell morphogenesis
GO:0030866 cortical actin cytoskeleton organization
GO:0035331 negative regulation of hippo signaling
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0070062 extracellular exosome
GO:0090443 FAR/SIN/STRIPAK complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7k36, PDBe:7k36, PDBj:7k36
PDBsum7k36
PubMed33633399
UniProtQ5VSL9|STRP1_HUMAN Striatin-interacting protein 1 (Gene Name=STRIP1)

[Back to BioLiP]