Structure of PDB 7aea Chain I

Receptor sequence
>7aeaI (length=107) Species: 9606 (Homo sapiens) [Search protein sequence]
MLLFCPGCGNGLIVEEGQRCHRFSCNTCPYVHNITRKVTNRKYPKLKEVD
DVLGGAAAWENVDSTAESCPKCEHPRAYFMQLQTRSADEPMTTFYKCCNA
QCGHRWR
3D structure
PDB7aea Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states.
ChainI
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN I C97 C98 N99 C97 C98 N99
BS02 ZN I C5 C25 C5 C25
Gene Ontology
Molecular Function
GO:0001056 RNA polymerase III activity
GO:0003676 nucleic acid binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
GO:0006383 transcription by RNA polymerase III
GO:0006386 termination of RNA polymerase III transcription
GO:0045087 innate immune response
GO:0051607 defense response to virus
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005666 RNA polymerase III complex
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7aea, PDBe:7aea, PDBj:7aea
PDBsum7aea
PubMed33558764
UniProtQ9Y2Y1|RPC10_HUMAN DNA-directed RNA polymerase III subunit RPC10 (Gene Name=POLR3K)

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