Structure of PDB 6xz7 Chain I

Receptor sequence
>6xz7I (length=134) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
YVKLQVAAGMANPSPPVGPALGQQGVNIMEFCKAFNAKTDSIEKGLPIPV
VITVYADRSFTFVTKTPPAAVLLKKAAGIKSGSGKPNKDKVGKISRAQLQ
EIAQTKAADMTGADIEAMTRSIEGTARSMGLVVE
3D structure
PDB6xz7 Insights into the improved macrolide inhibitory activity from the high-resolution cryo-EM structure of dirithromycin bound to theE. coli70S ribosome.
ChainI
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna I K10 Q12 Q30 P75 A77 K81 G89 S90 G91 K92 P93 N94 K95 K113 M117 T118 G119 A124 R127 S128 G131 T132 S135 M136 K3 Q5 Q23 P68 A70 K74 G82 S83 G84 K85 P86 N87 K88 K106 M110 T111 G112 A117 R120 S121 G124 T125 S128 M129
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
GO:0070180 large ribosomal subunit rRNA binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0006415 translational termination
GO:0015968 stringent response
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6xz7, PDBe:6xz7, PDBj:6xz7
PDBsum6xz7
PubMed32144191
UniProtP0A7J7|RL11_ECOLI Large ribosomal subunit protein uL11 (Gene Name=rplK)

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