Structure of PDB 6v92 Chain I

Receptor sequence
>6v92I (length=293) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
NYEQEAQKLEEKALRFLAKQTHPVIIPSFASWFDISKIHEIEKRSNPDFF
NDSSRFKTPKAYKDTRNFIINTYRLSPYEYLTITAVRRNVAMDVASIVKI
HAFLEKWGLINYQIDPRTKPSLIGPSFTGHFQVVLDTPQGLKPFLPKEFP
VNLTIKKNVYDSAQDFNALQDESRNSRQIHKVYICHTCGNESINVRYHNL
RARDTNLCSRCFQEGHFGANFQSSDFIRLENNGNSVKKNWSDQEMLLLLE
GIEMYEDQWEKIADHVGGHKRVEDCIEKFLSLPIEDNYIREVV
3D structure
PDB6v92 Architecture of the chromatin remodeler RSC and insights into its nucleosome engagement.
ChainI
Resolution20.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide I H261 N265 H186 N190
BS02 ZN I C260 C283 C286 C185 C208 C211
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0042393 histone binding
GO:0046872 metal ion binding
Biological Process
GO:0006303 double-strand break repair via nonhomologous end joining
GO:0006325 chromatin organization
GO:0006337 nucleosome disassembly
GO:0006338 chromatin remodeling
GO:0006355 regulation of DNA-templated transcription
GO:0006368 transcription elongation by RNA polymerase II
GO:0045893 positive regulation of DNA-templated transcription
Cellular Component
GO:0000785 chromatin
GO:0005634 nucleus
GO:0016514 SWI/SNF complex
GO:0016586 RSC-type complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6v92, PDBe:6v92, PDBj:6v92
PDBsum6v92
PubMed31886770
UniProtP43609|RSC8_YEAST Chromatin structure-remodeling complex protein RSC8 (Gene Name=RSC8)

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