Structure of PDB 6uwt Chain I

Receptor sequence
>6uwtI (length=660) Species: 1496 (Clostridioides difficile) [Search protein sequence]
EDLDTDNDNIPDSYERNGYTIKDLIAVKWEDSFAEQGYKKYVSNYLESNT
AGDPYTDYEKASGSFDKAIKTEARDPLVAAYPIVGVGMEKLIISTNEHAS
TDQGKTVSRATTNSKTESNTAGVSVNVGYQNGFTANVTTNYSHTTDNSTA
VQDSNGESWNTGLSINKGESAYINANVRYYNTGTAPMYKVTPTTNLVLDG
DTLSTIKAQENQIGNNLSPGDTYPKKGLSPLALNTMDQFSSRLIPINYDQ
LKKLDAGKQIKLETTQVSGNFGTKNSSGQIVTEGNSWSDYISQIDSISAS
IILDTENESYERRVTAKNLQDPEDKTPELTIGEAIEKAFGATKKDGLLYF
NDIPIDESCVELIFDDNTANKIKDSLKTLSDKKIYNVKLERGMNILIKTP
TYFTNFDDYNNYPSTWSNVNTTNQDGLQGSANKLNGETKIKIPMSELKPY
KRYVFSGYSKDPLTSNSIIVKIKAKEEKTDYLVPEQGYTKFSYEFETTEK
DSSNIEITLIGSGTTYLDNLSITELNSTPEILDEPEVKIPTDQEIMDAHK
IYFADLNFNPSTGNTYINGMYFAPTQTNKEALDYIQKYRVEATLQYSGFK
DIGTKDKEMRNYLGDPNQPKTNYVNLRSYFTGGENIMTYKKLRIYAITPD
DRELLVLSVD
3D structure
PDB6uwt Structure of the cell-binding component of theClostridium difficilebinary toxin reveals a di-heptamer macromolecular assembly.
ChainI
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA I D222 D224 E231 N260 E263 D273 D6 D8 E15 N44 E47 D57
BS02 CA I D220 D222 D224 I226 E231 D4 D6 D8 I10 E15
Gene Ontology
Biological Process
GO:0051260 protein homooligomerization
Cellular Component
GO:0005576 extracellular region

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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6uwt, PDBe:6uwt, PDBj:6uwt
PDBsum6uwt
PubMed31896582
UniProtO32739

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