Structure of PDB 6rfl Chain I

Receptor sequence
>6rflI (length=773) Species: 502057 (Vaccinia virus GLV-1h68) [Search protein sequence]
DSKETILIEIIPKIKAYLLDANISPKSYDDFISRNKNIFVINLYNVSTIT
EEDIRLLYTTIEQNIDADDQTLVAIFSYIGYKFEQAVKEEISTSLSFNDK
NTTDEMTYNLYDLFFNTLDMYLRQKKISILVNDDVVIVSYKPEIKKIPFN
MKNLLPYLEKNLDQLRFSKKYLDFAYLCRHIGIPISKKKYNVRYVFLYKI
DGLSIPIIIKDFLDVKYVYLENTGKIYKNSFSEDHNNSLSDWGKVIIPLL
KDRHLYSYIFLSSYHLHSYYTDLIARDEPVFVKRKKLDIIEIDEPEAWKR
DVRVEFAPCEHQIRLKEAMKVDANYFTKINNFANEFIYYEDGVAYCRVCG
INIPIFNLDAADVIKNTVIVSTFNKTIFLSEPYSYFVHSQRFIFNIIMSF
DNIMKSQTWVMKYNINRLILNFLIDINSRRQEYEKKFSSEIKRGLFFLRL
SANLFETELFYVSKMLNLNYIVALVIILNSSADFIVSYMTSKNKTVEEST
LKYAISVVIYDFLVKTRICEKGSLDTIVLFTDVYTSIMPEELDLHFQRIT
LELRKLVSIQRSALEPNYDVESRGEELPLSALKFFDTSTIIVKTMAPVHT
CVEQKIVAPTPSVEPTDASLKNFKELTCDEDIKILIRVHDTNATKLVIFP
SHLKIEIERKKLIIPLKSLYITNTLKYYYSNSYLYVFRFGDPMPFEEELI
DHEHVQYKINCYNILRYHLLPDSDVFVYFSNSLNREALEYAFYIFLSKYV
NVKQWIDENITRIKELYMINFNN
3D structure
PDB6rfl Structural Basis of Poxvirus Transcription: Vaccinia RNA Polymerase Complexes.
ChainI
Resolution2.76 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna I Q125 K127 Y144 K187 K206 D231 K233 Y234 H252 N254 Y281 Q124 K126 Y140 K170 K189 D214 K216 Y217 H235 N237 Y264
BS02 ZN I C326 H328 C363 C309 H311 C346
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0016779 nucleotidyltransferase activity
Biological Process
GO:0006353 DNA-templated transcription termination
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6rfl, PDBe:6rfl, PDBj:6rfl
PDBsum6rfl
PubMed31835032
UniProtQ1PIU7

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