Structure of PDB 6j6n Chain I

Receptor sequence
>6j6nI (length=102) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
RGGISYDQLAKLSYEKTLRNLATQTQNSSKQDKVQKDTKTGKITIADDDK
LVNKLAVSLQSESKKRYEARKRQMQNAKTLYGVESFINDKNKQFNEKLSR
ES
3D structure
PDB6j6n Structures of the Catalytically Activated Yeast Spliceosome Reveal the Mechanism of Branching.
ChainI
Resolution3.86 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna I Y97 S104 K107 R175 Y176 R179 K180 Y6 S13 K16 R66 Y67 R70 K71
BS02 rna I R92 R179 M183 K199 Q202 F203 K206 R209 R1 R70 M74 K90 Q93 F94 K97 R100
Gene Ontology
Molecular Function
GO:0000384 first spliceosomal transesterification activity
GO:0000386 second spliceosomal transesterification activity
GO:0005515 protein binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0000974 Prp19 complex
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005829 cytosol
GO:0071004 U2-type prespliceosome
GO:0071006 U2-type catalytic step 1 spliceosome
GO:0071007 U2-type catalytic step 2 spliceosome
GO:0071008 U2-type post-mRNA release spliceosomal complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6j6n, PDBe:6j6n, PDBj:6j6n
PDBsum6j6n
PubMed30879786
UniProtP53277|SYF2_YEAST Pre-mRNA-splicing factor SYF2 (Gene Name=SYF2)

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