Structure of PDB 6huf Chain I

Receptor sequence
>6hufI (length=171) Species: 9606 (Homo sapiens) [Search protein sequence]
YLIKFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKTIYRNDKR
IKLQLWDTAGLERFRSLTTAFFRDAMGFLLLFDLTNEESFLNVRNWISQL
KTHAYSENPDIVLCGNKSDLEDERVVAAAEARQLAEHYGIPYFETSAANG
TNISQAIEMLLDLIMKRMERS
3D structure
PDB6huf Coping with strong translational noncrystallographic symmetry and extreme anisotropy in molecular replacement with Phaser: human Rab27a.
ChainI
Resolution2.82 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG I T23 T41 T16 T34
BS02 GNP I S18 G21 K22 T23 S24 S36 T40 T41 G67 N123 K124 D126 S11 G14 K15 T16 S17 S29 T33 T34 G60 N116 K117 D119
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:6huf, PDBe:6huf, PDBj:6huf
PDBsum6huf
PubMed30950405
UniProtP51159|RB27A_HUMAN Ras-related protein Rab-27A (Gene Name=RAB27A)

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