Structure of PDB 6gcs Chain I

Receptor sequence
>6gcsI (length=180) Species: 4952 (Yarrowia lipolytica) [Search protein sequence]
APPAGFRIHRPATWEESEEGALSKATKYFLLAEMFRGLYVVLEQFFRAPY
TIYYPFEKGPVSPRFRGEHALRRYPSGEERCIACKLCEAICPALAITIDA
EERIDGSRRTTKYDIDMTKCIYCGYCQESCPVDAIVETPNVEYATETREE
LLYNKEKLLANGDKWELELQYALDADAPYR
3D structure
PDB6gcs Cryo-EM structure of respiratory complex I at work.
ChainI
Resolution4.32 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.6.99.3: Deleted entry.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SF4 I H118 C140 P141 I145 C169 I170 C172 G173 Y174 C175 H69 C91 P92 I96 C120 I121 C123 G124 Y125 C126
BS02 SF4 I C130 I131 A132 C133 K134 C136 C179 C81 I82 A83 C84 K85 C87 C130
Gene Ontology
Molecular Function
GO:0003954 NADH dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0016651 oxidoreductase activity, acting on NAD(P)H
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
GO:0032981 mitochondrial respiratory chain complex I assembly
Cellular Component
GO:0005739 mitochondrion
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6gcs, PDBe:6gcs, PDBj:6gcs
PDBsum6gcs
PubMed30277212
UniProtQ9UUT8

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