Structure of PDB 6dec Chain I

Receptor sequence
>6decI (length=209) Species: 9913 (Bos taurus) [Search protein sequence]
EPPMNPTKNREKIVEVMQAVLTLYAQGLLTSGDGVTHICYEGFSLPHIAG
RDITRYLIKLLLLRAFNHSADFETVRMIKEKLCYVGYNIEQEQKLALETT
VLVESYTLPDGRIIKVGGERFEAPEALFQPHLINVEGVGVAELLFNTIQA
ADIDEFYKHIVLGSTMYPLPSRLERELKQLYLERVLKGDVEKLSKFPPRR
KHMVFLGGA
3D structure
PDB6dec Structure of the nucleation-promoting factor SPIN90 bound to the actin filament nucleator Arp2/3 complex.
ChainI
Resolution4.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP I G160 D161 G186 G306 M309 G32 D33 G50 G163 M166
Gene Ontology
Molecular Function
GO:0003779 actin binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0051015 actin filament binding
Biological Process
GO:0010592 positive regulation of lamellipodium assembly
GO:0034314 Arp2/3 complex-mediated actin nucleation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:1905168 positive regulation of double-strand break repair via homologous recombination
GO:2001032 regulation of double-strand break repair via nonhomologous end joining
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005885 Arp2/3 protein complex
GO:0005938 cell cortex
GO:0035861 site of double-strand break
GO:0042995 cell projection

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6dec, PDBe:6dec, PDBj:6dec
PDBsum6dec
PubMed30322896
UniProtA7MB62|ARP2_BOVIN Actin-related protein 2 (Gene Name=ACTR2)

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