Structure of PDB 6cnl Chain I

Receptor sequence
>6cnlI (length=183) Species: 9606 (Homo sapiens) [Search protein sequence]
AKATRHIFLIRASQYHRTLTPLGREQAELTGLRLASLGLKFNKIVHSSMT
RAIETTDIISRHLPGVCKVSTDLLREGAPIEPDPPPEAVQYYEDGARIEA
AFRNYIHRADARQEEDSYEIFICHANVIRYIVCRALQFPPEGWLRLSLNN
GSITHLVIRPNGRVALRTLGDTGFMPPDKITRS
3D structure
PDB6cnl Functional role of PGAM5 multimeric assemblies and their polymerization into filaments.
ChainI
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.16: protein-serine/threonine phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide I D184 P185 P245 R251 D83 P84 P139 R145
BS02 peptide I V195 Y198 E199 V89 Y92 E93
BS03 peptide I I212 H213 R214 Q243 G268 I106 H107 R108 Q137 G162
BS04 MG I R104 R152 H230 R11 R51 H124
BS05 MG I L254 N255 G276 L148 N149 G170
External links
PDB RCSB:6cnl, PDBe:6cnl, PDBj:6cnl
PDBsum6cnl
PubMed30705304
UniProtQ96HS1|PGAM5_HUMAN Serine/threonine-protein phosphatase PGAM5, mitochondrial (Gene Name=PGAM5)

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