Structure of PDB 6asb Chain I

Receptor sequence
>6asbI (length=121) Species: 9606 (Homo sapiens) [Search protein sequence]
RRRRTRCRRCRACVRTECGDCHFCRDMKKFGGPGRMKQSCLLRQCTAPVL
PHTAVCLLCGEAGKEDTVEGEEEKFGLSLMECTICNEIVHPGCLKMGKAE
GVINAEIPNCWECPRCTQEGR
3D structure
PDB6asb DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.
ChainI
Resolution2.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna I R35 R36 R38 K69 Q70 S71 R75 N118 R3 R4 R6 K37 Q38 S39 R43 N86 PDBbind-CN: Kd=1.5uM
BS02 dna I R33 R34 R35 T37 R67 M68 Q70 P83 H84 R1 R2 R3 T5 R35 M36 Q38 P51 H52 PDBbind-CN: Kd=1.5uM
BS03 ZN I C39 C42 C45 C77 C7 C10 C13 C45
BS04 ZN I C53 C56 C72 C21 C24 C40
BS05 ZN I C88 C91 H122 C125 C56 C59 H90 C93
BS06 ZN I C114 C117 C148 C82 C85 C116
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:6asb, PDBe:6asb, PDBj:6asb
PDBsum6asb
PubMed29276034
UniProtQ6PCT2|FXL19_HUMAN F-box/LRR-repeat protein 19 (Gene Name=FBXL19)

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